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A combination of extracellular glutamate and cystine enables cultured rat astrocytes to most efficiently synthesize GSH, while cultured rat neurons prefer glutamine and cysteine as extracellular precursors for GSH synthesis (Kranich et al
L-Cystine A vital amino acid that aids in skin regeneration and fading of dark spots and acne scars
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This was done in the presence of the CI-linked substrates pyruvate (5 mM), malate (2 mM) and in the absence of ADP (2.5 mM) followed by the addition of cytochrome c (10 M) to test for the integrity of the mitochondrial outer membrane (cytochrome c control efficiency)
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