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Obwohl der Mechanismus der His-Phe-Arg-Trp-Auslsung der Erektionsreaktion noch nicht vollstndig aufgeklrt ist, wird angenommen, dass das Zentralnervensystem und wahrscheinlich die Bindung an MC3-R und/oder MC4-R beteiligt sind.The minimum peptide fragment of the native -MSH required for an erection reaction is the central tetrapeptide sequence His 6 -Phe 7 -Arg 8 -Trp 9 (SEQ ID 1)