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3.3.3 Receptors mediated mitophagy activators Panax notoginseng saponins (PNS), the primary ingredient from Panax notoginseng, exhibits extensive therapeutic effects in cardiovascular diseases (Liu et al., 2014), lung cancer (Yang et al., 2016) and diabetes (Uzayisenga et al., 2014)

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To validate their ability to differentiate into osteogenic and adipogenic lineages, the expression of RUNX-2, ALP, FABP4, and PPAR were evaluated using real time polymerase chain reaction (RT-PCR) as reported [43]