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They certainly deliver value to some: The minority of patients who are persistent long enough to achieve clinically meaningful weight loss

C., Kumar, A., Placone, J

Nat Rev Neurosci 9:182194 Boehme M, Van de Wouw M, Van Sandhu K et al (2018) Targeting the gut microbiome to reverse microglia activation and stress-induced immune priming in ageing

It achieves this by modulating the activity of various enzymes and growth factors involved in the wound healing cascade, including metalloproteinases, which are essential for breaking down and remodeling damaged tissue