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Receptor subtype-selective binding and functional assays typically comparing synephrine's potency at beta-1, beta-2, and beta-3 adrenergic receptor subtypes using cAMP accumulation or radioligand displacement methods are used to characterise its relative selectivity profile

[4] Secondly, there may be a need to increase the vertical dimension of the lower face to prevent overclosure of the mouth and formation of deep skin folds

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