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Gluten is a sticky, storage protein that is challenging for the digestive tract because it binds to the small intestinal wall where it can cause digestive and immune system disorders

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Non-pharmacological approaches involve addressing the underlying causes of cirrhosis and adhering to the validated TrACE (Treating causes, Ameliorating modifiable factors, Coping mechanisms, and Empathizing) model, particularly used to manage fatigue in primary biliary cholangitis

Under normal conditions, zonula occluden 1 (ZO-1) forms tight junction (TJs) complexes with the help of actin filament binding to form selective permeability of intestinal barrier [84]