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Excluding the trial judged at high risk of bias for efficacy outcomes likewise did not materially change the estimate (SMD 1.32, 95% CI 2.33 to 0.31

PRODUCT INFORMATION Packaging: 5 x 10 mL vials in one package Composition: Lecithin, riboflavin, bromelain Method of Administration: Mesotherapy fat lipolysis, Direct Injection Injection depth: Subcutaneous fatty layer Needle size : 30G Usage per point: 1 mL with a point interval of 1 cm (face), 1.5-2 mL with a point interval of 1.5-2 cm Maximum dosage: 50-100 mL per treatment session, depending on the treated area Precautions Avoid injecting the area around the eyes

Compared with placebo, the tested formulation produced a more pronounced reduction in thigh circumference and in fat mass as measured by dual-energy X-ray absorptiometry