Society has long believed that addiction is a moral problem when it is, in fact, a very real disease with biological risk factors like genetics, psychological risk factors like early childhood trauma, and sociological or environmental risk factors like poverty and unemployment, explains Anna Lembke, MD, a professor of psychiatry and addiction medicine at Stanford University and the author of Dopamine Nation: Finding Balance in the Age of Indulgence
To investigate further, the MHRA and UK Biobank are working together to understand if there is a genetic link between GLP-1s and drug-induced acute pancreatitis, similar to that with immunosuppressant drug thiopurine
This could be due to enhancement of hepatic amino-acid catabolism with hepatic glucagon receptor activation
The legal process includes investigating evidence, negotiating settlements, or moving cases to multidistrict litigation (MDL)