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In the second and third group each of the bone defects was treated locally with either 2 ml autologous bone marrow (7 th post-operative day) or TRIS-BPC157 (10 g/kg b.w

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Its well-known adverse events, e.g., interstitial pulmonary fibrosis, seizures, liver veno-occlusive disease, or sinusoidal obstruction syndrome [96] seem to be caused by glutathionyl-tetrahydrothiophene, a metabolite that derives from the irreversible GSH conjugation [97,98]