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Moreover, age has found to be positively correlated with higher AC/FC ratio

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By 2008, the proposition that anti-manic drugs attenuated kinases for their therapeutic effect was put forth, including key kinases GSK3 (inhibited by lithium, valproate and ECT) and PKC (inhibited by chronic lithium, valproate and ECT) (Machado-Vieira et al., 2023)

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