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For example, variants in GLP1R (rs6923761) and MC4R (rs17782313) have been associated with differential weight response in some studies, though genetics does not determine exact treatment outcomes

The Zepbound label specifically includes a warning to monitor for depression and suicidal thoughts or behaviors

Given the fact that diabetes is frequently associated with diabetic retinopathy and that this comorbidity can serve as a potential confounding factor, researchers separately analyzed the semaglutide-related risk of visual impairment in patients with and without type 2 diabetes

Cree said that's consistent with previous studies on GLP-1s in adults with obesity