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J Am Coll Cardiol 2023;81:1902-14.ArticlePubMed 113

While previous studies highlighted some of these risks in patients with diabetes, this study from the University of British Columbia is the first large, population-level study to examine adverse gastrointestinal events in non-diabetic patients using the drugs specifically for weight loss

While the exact cause of PCOS is unknown, factors contributing to its onset include chronic inflammation, higher levels of androgens (male sex hormones that impede ovulation), weight gain, and insulin resistance, a precursor to prediabetes and Type 2 diabetes that impairs the bodys ability to use glucose efficiently