Under physiological conditions, ROS regulate specific cellular functions, although high levels lead to various forms of cellular damage to DNA, proteins, and lipids and ultimately affect oocyte quality and viability 57
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The manuscript highlights how DDSsincluding stimuli-responsive nanoparticles, targeted ligands, and biodegradable carriersenhance solubility, bioavailability, and tissue-specific delivery of urate-lowering agents (e.g., allopurinol and febuxostat) and anti-inflammatory therapies (e.g., colchicine and IL-1 inhibitors) (Chen Z
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