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However, species differences in skin permeability can significantly impact the relevance of the data obtained

In humans, IGF-I also increases renal blood flow and GFR by ~25% and causes volume expansion and sodium retention by a direct action on the renal tubules, with stimulation of rennin release and suppression of atrial natriuretic peptide secretion[364]

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That's a description of fit, not a recommendation - whether GLP-1 medication of any kind is appropriate for a given person is a clinical determination made by a licensed provider reviewing that person's actual health history, not something this article or any marketing page can establish in advance