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The results indicated a reduction in both gray and white matter regions after 1 year in the brains of patients who underwent chemotherapy, establishing a clear connection between white matter integrity, cognitive impairment, and chemotherapy ( Moreover, paclitaxel has been linked to detrimental effects on white matter integrity in the CNS

Systematic proteomic analysis of protein methylation in prokaryotes and eukaryotes revealed distinct substrate specificity

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Underlying conditions that can impair treatment response include hypothyroidism, polycystic ovary syndrome (PCOS), Cushing's syndrome, obstructive sleep apnea, and psychiatric conditions like binge eating disorder