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Gli endpoint istologici (risoluzione della MASH, miglioramento della fibrosi) sono surrogate endpoints: la riduzione della morbilit e mortalit epatica a lungo termine lendpoint clinico che conferir o negher lapprovazione definitiva sar valutata nella parte 2 dello studio

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Au cours du processus d'augmentation de la dose, les patients doivent s'adapter progressivement l'augmentation de la posologie du mdicament tout en continuant surveiller leur glycmie et leurs rponses physiques

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