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Combined with 82% liver fat reduction, improved insulin sensitivity, and comprehensive metabolic improvements, retatrutide alone may accomplish what researchers seek from the combination

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The clinical evidence increasingly suggests that obesity is a chronic condition requiring ongoing management, much like high blood pressure or diabetes

The eGFR of patients across both groups were primarily between with a mean eGFR of Most patients were taking antihypertensive medication and/or lipid-lowering drugs For CV history, only data for prior heart failure was provided, and of patients in the semaglutide group had prior heart failure compared to of the placebo group