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Research also notes that natural levels show a GHK-Cu decline with age, with levels falling by about 60% by age 60, a pattern linked to reduced healing, skin health, and regenerative capacity in the human body

Older adults, who often suffer from decreased hydrochloric acid in the stomach, and individuals with gastrointestinal (GI) disorders may have lower absorption of B12.2,4 Vitamin B12 deficiency may be characterized by megaloblastic anemia, fatigue, weakness, constipation, loss of appetite, soreness of the mouth or tongue, and weight loss

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