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coli to investigate their effects on GSH production, including the reduction of l-cysteine degradation, manipulation of the glucose storage pathway, and elimination of the biological degradation of GSH (Fig

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consequently, this discussion is divided into selective COX-2 inhibitors and non-selective COX inhibitors, as selective COX-2 blockade is hypothesised to confer superior anti-inflammatoryand thus antidepressantactivity 29