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The following sections will systematically elaborate on the proposed crosstalk mechanisms between ferroptosis and cuproptosis and explore corresponding synergistic therapeutic strategies, noting that many of these interactions require further experimental validation

In addition to working as an electron carrier, the oxidized cyt c also serves as a scavenger of reactive oxygen species (ROS) (Wang et al., 2003), a cardiolipin peroxidase (Kagan et al., 2005), and an apoptosis activator once released to the cytosol (Ow et al., 2008)

doi: 10.3390/cells12091263 41 ZhuJTangYWuQJiYCFengZFKangFW

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