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cAMP accumulation assay Peptide or small molecules stimulated cAMP accumulation was measured by a LANCE Ultra cAMP kit (PerkinElmer)

21 The clinical efficacy of PEA has been demonstrated in a study of 30 women taking 600mg of ultramicronized-palmitoylethanolamide (um-PEA) twice daily followed by co-micronized palmitoylethanolamide/polydatin (m(PEA/PLD)) (440mg+40mg) micro granules twice daily for 80 days

Seidu S, Mellbin L, Kaiser M, Khunti K