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Description

Under hypoglycaemic conditions, catecholaminergic neurons in the NTS can regulate agouti-related peptide (AgRP)/pro-opiomelanocortin (POMC) neuronal activity in the arcuate nucleus (ARC) via ascending projections, thereby driving feeding behaviour (56)

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Escalation Strategy To reduce side effects, trial participants start at low doses and escalate slowly

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Generic advice has limits One person may tolerate a single glass of wine with dinner several days after an injection

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Sleep Disturbance : GERD symptoms often worsen at night when lying down

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