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What the Research Shows About Tirzepatide Blood Pressure Effects Clinical studies using both standard office measurements and ambulatory blood pressure monitoring have found that tirzepatide is associated with: Lower average systolic blood pressure Smaller but consistent reductions in diastolic pressure Improvements that become more noticeable over several months On average, systolic blood pressure reductions tend to fall within the midsingle-digit mmHg range, which can be clinically meaningful, particularly for people with obesity-related hypertension

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In 1997, it received a second approval for the treatment of idiopathic growth hormone deficiency in children

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