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Semaglutide (weekly injectable) Dosing frequency: Once weekly, same day each week Half-life: approximately 7 days (165 to 184 hours) Peak concentration: 1 to 3 days after injection Recommended timing approach: Most flexible of all GLP-1 formulations due to the long half-life

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In the big Ozempic trials, about a third of people were super responders, but as many as one in six didnt lose significant weight at all, even after taking the drug for more than a year

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