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Samples were processed as follows: the proteins were precipitated with acetone/TCA (Sigma-Aldrich)

In the first trimester of pregnancy, macrophages are the second most abundant leukocyte population in the decidual layer of the placenta ( ), nuclear factor-k-B binding (NF-kB), and interferon regulatory factors (IRFs) ( 4.4 Role of melatonin as an antioxidant and anti-inflammatory in the placenta during oxidative stress Melatonin has a wide array of functions due to its ubiquitous nature

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