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Par exemple, chez des souris rendues obses et ayant dvelopp une statose hpatique, une supplmentation pendant 4 semaines a diminu la quantit de lipides prsents dans le foie en facilitant leur oxydation et en bloquant leur production 5

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Although many preclinical studies suggest that GLP-1R agonism can act directly on neurons to prevent cell death, this neuroprotective property may be secondary to reduced glucotoxicity and inflammation in the brain that can result from weight loss and improvements in glycemic control (Berkseth et al., 2014)

Therapeutic Potential of Creatine Supplementation in Diseases Considering that the primary action of creatine supplementation occurs at the muscular level, various studies have investigated its potential effects on myopathies [95]