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Whether rapid or gradual, losing significant weight can lead to loose, excess skin anywhere on your body

An observational 2026 study of nearly 95,500 people in Sweden who already had depression, anxiety or both found that semaglutide users were less likely to experience worsening symptoms, self-harm and other serious mental health outcomes

(Rybelsus, an earlier oral semaglutide product, is approved for type 2 diabetes but not for weight management.) According to the company's announcement, Novo Nordisk plans a full U.S