Por otro lado, los frmacos de accin prolongada, permiten un mayor control de la glucemia basal, como la exenatida de liberacin prolongada, liraglutida, dulaglutida, albiglutida y por ltimo semaglutida, aprobada recientemente por la FDA 56 .Adems, se ha demostrado que los GLP1-RA disminuyen el riesgo de eventos cardiovasculares al influir positivamente en factores de riesgo como obesidad, presin arterial y perfil lipdico 15
Also, these meals have to be spread across the day
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The six cellular pathways to longevity are the same pathways to chronic metabolic disease: Glycation Oxidative stress Inflammation Mitochondrial dysfunction Insulin resistance Membrane instability And none of these pathways are druggable, except maybe inflammation, and that may be downstream of the other five
