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Large doses of folic acid may also partially mask or worsen vitamin B deficiency by correcting anemia while allowing neurological damage to progress

Zhang Y, Gao Y, Fang K, Ye JJ, Ruan YH, Yang XJ, et al

The toxins, enzymes and metabolites of bacteria (predominantly Gram-negative anaerobic) present in the dental plaque play a key role in the initiation of the inflammatory process, but the exact pathomechanism is far from being understood in detail (5-8)