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For human studies, the study sample size and design, GLP-1R agonist/antagonist or DPP-IV inhibitor name, dose, administration method and duration, assessments, and main results were extracted

NAC was also found to be safe and well-tolerated

The most significant factor affecting thyroid functioning was vitamin B9 or folate

Previous solution-phase studies and computational models of GLP-1 and exendin-4 indicated that the N-terminal had a type II beta turn, but more recent results concluded that the secondary structure of peptides, when bound to class B GPCRs of which the GLP-1R is one, is helical all through the sequence (41)