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We counteract this

This finding is important because it suggests that aging effects on the disc may involve a relatively uniform set of factors from which many cLBP patients deviate

In addition to GLP-1R, the peptide itself appears to be important for this interaction, as the increased levels of GLP-1 after DPP-IV inhibition (with sitagliptin) reduce nicotine consumption in male mice (Tuesta et al., 2017)

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