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On July 22, 2025, Huadong Medicines wholly-owned subsidiary, Sinopharm Huadong, announced that its self-developed oral small-molecule GLP-1 receptor full agonist, HDM1002, received FDA clearance for clinical trials in the U.S., intended for weight management in individuals with overweight or obesity

However, where the epidermis was severely damaged, the layer of tissue containing TGM2 was exposed on the surface (Figure 6c)

If you notice these or any other concerning symptoms, contact your healthcare provider

Treatment indications continue to expand The mechanisms underlying incretin-based therapies remain incompletely understood