Insulinotropic glucagon-like peptide I receptor expression in glucagon-producing alpha-cells of the rat endocrine pancreas
When enough of them break simultaneously, the peptide loses its ability to fit properly into the GLP-1 receptor
In fact, GLP-1 users risk losing between 40 and 60 percent of their lean mass (which also includes organs, bones, fluids, and even water stored in fat tissue)
doi: 10.3389/fendo.2024.1330936 Received 31 October 2023 Accepted 02 January 2024 Published 06 February 2024 Volume 15 - 2024 Edited by Julianne Hall, Quinnipiac University, United States Reviewed by Eric Morris Bomberg, University of Minnesota, United States Michihiro Takahashi, Takahashi Psychiatric Clinic, Japan Updates Copyright 2024 Chen, Cai, Zou and Fu