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Lifestyle modifications should be the first-line approach and include: Eating smaller, more frequent meals rather than large portions that overwhelm the already-slowed digestive system Avoiding eating within 2-3 hours of bedtime to allow adequate time for gastric emptying before lying down Elevating the head of the bed by 6-8 inches using blocks or a wedge pillow to reduce nocturnal reflux Identifying and avoiding trigger foods such as caffeine, alcohol, chocolate, spicy foods, citrus, and high-fat meals Maintaining an upright posture for at least 2-3 hours after meals Wearing loose-fitting clothing that doesn't compress the abdomen Pharmacological management may be appropriate for patients with persistent symptoms despite lifestyle modifications

Acetyl-L-carnitine deficiency as a cause of altered nerve myo-inositol content, Na,K- ATPase activity, and motor conduction velocity in the streptozotocin-diabetic rat Metabolism 1996

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The most common side effects experienced were nausea, diarrhoea and vomiting