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Computational modeling of the kinetics and mechanism of the new generation of glutathione peroxidase nanomimic: selenosubtilisin and tellurosubtilisin

These initial clinical results support the concept of DPP1 inhibition as a potential therapeutic strategy across multiple inflammatory diseases that involve excessive NSP secretion or neutrophil dysregulation and hyperresponsiveness

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SNCA A53T and Gpx4 fl/fl were crossbred to obtain SNCA A53T / Gpx4 +/fl double transgenic hemizygous mice