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An examination of the ratios of plasma to brain total acylcarnitine levels showed a significant decrease in this ratio in E4 mice after challenge with L-carnitine but not in E3 mice, while there was a trend in E2 mice (Figure 9C)

The habenula has notably high levels of MOR (medial habenula) [44] and also expresses KOR (lateral habenula) [45], is implicated in aversive states [46] including NPW [20], and modulates DA release [47, 48]