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Is this a thing or am I losing my mind? Roberts, Vega and Massarone are pioneers in what Nicholas Reville, co-founder and executive director of the Center for Addiction Science, Policy and Research, predicts will be the biggest breakthrough in addiction treatment of all time: GLP-1 drugs

So the chemically castrated patient, meaning they have no testosterone so if you treat a patient who has no testosterone and you take them from zero testosterone to normal testosterone, so to take them from, let's say, zero to 350, um, during that climb from zero to 350, you can increase theoretically, the risk of exasperating a prostate cancer that's pre pre-existing was the fear

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However, with IBD-current biologic therapies, all these mean some patients primary non-responders, experience a loss of response, intolerance or side effects, defining the urgent unmet need for novel treatments (13, 14)