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Additionally, the role of non-classical ferroptosis suppressors (e.g., FSP1, DHODH, and GCH1/BH4) in ADPKD is entirely unexploredwhether these pathways compensate for GPX4 downregulation in cystic kidneys or if their dysfunction exacerbates ferroptosis susceptibility remains unknown, limiting the development of multi-targeted interventions

C., Di Vincenzo, C., Bellantoni, D., Napoli, E., Valeri, G., & Vicari, S

RPE is particularly susceptible to oxidative stress due to its role in phagocytosis of photoreceptor outer segments 2

BPC 157 remains a peptide of high interest in research for its potential regenerative properties