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Sticking to this schedule helps your body develop a steady-state response, which is particularly important during dose escalation phases when your tolerance and clinical benefits are still stabilizing

PDE5 is an enzyme that is found in many parts of the body including in the smooth muscle of the corpus cavernosum, prostate, bladder, the vascular and visceral smooth muscle, skeletal muscle, urethra, platelets, kidney, lung, cerebellum, heart, liver, testis, seminal vesicle, and pancreas