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Under resting conditions, ASC is S-glutathionylated (notably at Cys171), a modification that impairs ASC oligomerization and prevents spontaneous inflammasome formation 67

PMCID: PMC10925889 Gilron I, DeBow C, Elkerdawy H, Khan JS, Salomons TV, Duggan S, Tu D, Holden RR, Milev R, Buckley DN, Moulin DE (2024) PRECISE trial (Pain relief combination intervention StratEgies): protocol for the clinical trial of a pregabalin-melatonin combination for fibromyalgia