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Absorption of oral glutathione can be inconsistent due to the range of factors that impact the digestive system, including stomach acid levels, enzyme activity, gut inflammation and individual differences in metabolism

The use of targeted nanocarriers solves the problems of both insufficient brain penetration of hydrophilic therapeutic molecules and high treatment doses inducing side-effects at the periphery [21, 26]

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Targeting NOX4 alleviates sepsis-induced acute lung injury via attenuation of redox-sensitive activation of CaMKII/ERK1/2/MLCK and endothelial cell barrier dysfunction