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While foods like grass-fed beef, dairy products and fish supply a good dose of vitamin B12, some people abstain from eating these foods or have a harder time absorbing and actually utilizing this nutrient due to digestive/metabolic limitations

In individuals with obesity, the skin may have been stretched out for years to accommodate larger fat volumes, which can result in a loss of elasticity and slower spring back after significant weight loss

Interventional approaches such as gastric peroral endoscopic pyloromyotomy (G-POEM) and sacral nerve stimulation (SNS) have shown feasibility in severe gastroparesis and anorectal dysfunction and merit assessment in dedicated SSc trials [87]

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