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We extend these findings by showing that use of SGLT2is is cost-effective regardless of their effects on glucose levels, suggesting that existing restrictions on their use may not be justified from a health economic perspective

doi: 10.2337/db20-0586 133 KirtipalNSeoYSonJLeeS

The endothelial glycocalyx prevents solutes to reach the endothelium not only by providing a physical barrier, but also due to its negative charges [44,45,46]