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Common side effects include: Nausea Vomiting Diarrhea Constipation Abdominal pain These side effects are often temporary and may subside as your body adjusts to the medication

Red meat, eggs, cruciferous vegetables (broccoli, cabbage, cauliflower), garlic, and onions are major contributors

This creates a clinical flow where patients initiate on oral therapy, stabilize, and either remain on pills or step up to higher-efficacy injectables based on their clinical needs, a tiered treatment model that expands the overall market rather than simply redistributing it

Clinical Trials & Approval The clinical development phase begins with Investigational New Drug (IND) submissions and proceeds through Phase I trials for safety and pharmacokinetics, Phase II for dose optimization and early efficacy, and Phase III for large-scale confirmation of therapeutic benefits