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Bupropion is also used as a smoking cessation aid and to treat depression, though Contrave is not approved for those uses

& McCormack, J

Due to their low toxicity and superior biocompatibility, phytocompound-derived medicines have shown a rise in demand in recent years 2

The SURMOUNT-1 trial (*NEJM*, 2022) showed participants on 15mg Tirzepatide lost an average of 22.5% of their body weight at 72 weeks -- roughly 5 percentage points more than Semaglutide achieves