semaglutide and irregular periods GLP-1 RAs linked to broad menstrual adverse event signals in reproductive-aged patients Wegovy and Periods: What Real

Safety and efficacy of once-weekly efruxifermin versus placebo in metabolic dysfunction-associated steatohepatitis (HARMONY): 96-week results from a multicentre, randomised, double-blind, placebo-controlled, phase 2b trial

To address several of the studys limitations, future research should examine the comparative effectiveness of treatments for obesity in patients who discontinue their novel GLP-1 receptor agonists (RA) or dual-RA medication, the researchers conclude

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The mechanism may involve modulation of somatostatin (GH inhibitory hormone) release from the hypothalamus, or interaction with GHRH neurons