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Acute JNK activation can be pro-apoptotic (e.g., in response to TNF- or oxidative stress), but it also plays essential roles in cell survival, metabolism, and tissue repair depending on the duration of activation and the cellular environment (70)

General wellness and longevity Some researchers use GHK-CU as a general longevity compound based on its broad gene expression effects favoring tissue maintenance and repair

rhizoma could be used food during times of famine ( The primary species of Polygonati rhizoma include Polygonatum cyrtonema Hua (PCH), Polygonatum sibiricum Red., and Polygonatum kingianum Coll

doi: 10.1016/j.plefa.2004.03.009 404 LengertNDrosselB