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- India as a global pricing anchor As seen in APIs and vaccines, India could once again reset global reference pricing for obesity and diabetes drugs -Margin compression vs volume expansion The value pool is shiftingfrom per-unit profitability to patient scale Competitive differentiation evolves -Future moats will likely depend on: Clinical outcomes & next-gen formulations Delivery innovation (oral GLP-1, long-acting injectables) Integrated care ecosystems

To test whether the protection of Ppara Hep mice against APAP-induced liver injury relied on the alteration of APAP metabolism, the expression of phase I, II, and III hepatic metabolizing enzymes was examined

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doi: 10.1210/en.2018-00004 33 SelvarajahVRobertsonDHansenLJermutusLSmithKCoggiAet al