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Authors' contributions JBA was the primary organizer of the study, did the initial data analysis, and was the primary author

Protective mucus in the GI tract consists of a sticky, negatively charged mesh that slows the diffusion of large, hydrophilic macromolecules while continuously turning over, thereby pulling material away from the epithelium

To evaluate the ability of molecules to interfere with aggregation of hCC while informing about cellular toxicity, cells were generated that produce and secrete WT and L68Q-hCC producing high-molecular weight complexes formed from the mutant protein