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By that point, the average semaglutide patient had lost 14.9% of their starting body weight, compared to 2.4% in the placebo group (Wilding et al., New England Journal of Medicine, 2021)

Clinical trials demonstrate average weight reduction of 12-15% of initial body weight over 68 weeks when combined with lifestyle modifications

Start your intake How GLP-1 Medications Trigger Gastrointestinal Changes GLP-1 receptor agonists work by slowing gastric emptying and enhancing intestinal glucose-dependent secretion of insulin